CrownSil™is an 18-crown ether-based chiral column that provides excellent separation capabilities for the separation of derivatives such as amino acids, amines, amino alcohols.
CrownSil™ , which has unique versatility, is a product further upgraded in separation and reproducibility by Dr. S.J. Kim, who commercialized ChiroSil for the first time in Korea, and is a high-quality HPLC column for chiral separation by Cellion Biomed Co., Ltd., which boasts excellent separation.
● Advantages of CrownSil™ and CrownSil-Me™:
• CrownSil™is a covalent combination of 18-crown ether and aminopropyl silica.
CrownSil-Me™ is covalently bonded to N-methylated aminopropyl silica.
• CrownSil™is optimized for reversed-phase separation, making it suitable for your next
separation.
High polar amino acids, amine compounds, and CrownSil-Me™ are better suited for:
Separation of hypopolar hydrophilic amino acids, β-amino acids, amines, amino alcohols.
CrownSil™includes:
• Specialized in the separation of a wide range of amino acids and amine compounds, the base
technology is the same as the existing ChiroSil series.
The same but with more advanced separation and symmetry.
• Exhibits a high coefficient of separation (α) as shown below, and has excellent symmetry to
prevent interference by tailing in the analysis of trace isomers
It is ineffective and provides accurate assays.
· By introducing a methyl group into CrownSil, this column is more optimized for separation.
Molecular weight of amine compounds derived from lipophilic amino acids and alkyl groups.
· CrownSil ME is a product that further enhances separation and symmetry.Innovation.
· As shown below, it exhibits a high coefficient of separation (α) and has excellent symmetry.
There is no interference effect from tailing in the analysis of small quantities of isomers.
It provides accurate analytical values.

Application of CrownSil™ and CrownSil-Me™:
It is very effective in separating various amino acids and amine derivatives as follows.
If you need a detailed separation chromatogram, please contact us and we will provide it right away. (sales@cellachrom.co.kr)
* α-Amino Acids:
Alanine, arginine, asparagine, aspartic acid, cysteine, dopa, ethionine, glutamic acid, histidine, fluorophenylalalanine, leucine, lysine, methionine, norleucine, norvaline, phenylalanine, phenyliglycine, serine, threonine, 4-tyrosine, thyroxine, tryptophan, valine, etc.
* Amine:
1,2,3,4-tetrahydro-1-naphthylamine, 1-phenylethylamine, 1-naphthylamine, 2-naphthylamine, 4-methyl-[1,1'-biphenyl]-4-amine, 2-phenylethylamine, 3-methylaniline, 4-methylaniline, etc.
* Amino Alcohols:
2-Amino-1-phenylethanol, 4-(2-amino-1-hydroxyethyl)phenol, 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol, 4-(2-amino-1-hydroxyethyl)-2-methoxyphenol, 2-amino-2-phenylethanol, 2-amino-2,3-dihydro-1H-indene-1-ol, 2-amino-1,2-diphenylethanol
* ß-blockers:
Acebutolol, Albuterol, Alprenolol, Atenolol, Bambuterol, Clenbuterol, Clenpropol, Fumoterol, Mabuterol, Oxprenolol, Pindolol, Propranolol.
- The CrownSil™ series is the new standard for crown ether chiral columns-
- Celachromium is the brand name of Celion Biomed Corporation. -
Contact: sales@cellachrim.co.kr
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