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CrownSil™ – is a Crown-Ether based Enhanced ChiroSil Column

CrownSil™is an 18-crown ether-based chiral column that provides excellent separation  capabilities for the separation of derivatives such as amino acids, amines, amino  alcohols.

CrownSil™ , which has unique versatility, is a product further upgraded in separation and reproducibility by Dr. S.J. Kim, who commercialized ChiroSil for the first time in Korea, and is a high-quality HPLC column for chiral separation by Cellion Biomed Co., Ltd., which boasts excellent separation.

● Advantages of CrownSil™ and CrownSil-Me™:

CrownSil™is a covalent combination of 18-crown ether and aminopropyl silica.

  CrownSil-Me™ is covalently bonded to N-methylated aminopropyl silica.

CrownSil™is optimized for reversed-phase separation, making it suitable for your next

   separation.

High polar amino acids, amine compounds, and CrownSil-Me™ are better suited for:

Separation of hypopolar hydrophilic amino acids, β-amino acids, amines, amino alcohols.



CrownSil™includes:

Specialized in the separation of a wide range of amino acids and amine compounds, the base

  technology is the same as the existing ChiroSil series.

  The same but with more advanced separation and symmetry.

Exhibits a high coefficient of separation (α) as shown below, and has excellent symmetry to

  prevent interference by tailing in the analysis of trace isomers

  It is ineffective and provides accurate assays.


CrownSil-Me™ includes:

·  By introducing a methyl group into CrownSil, this column is more optimized for separation.

   Molecular weight of amine compounds derived from lipophilic amino acids and alkyl groups.

·   CrownSil ME is a product that further enhances separation and symmetry.Innovation.

·   As shown below, it exhibits a high coefficient of separation (α) and has excellent symmetry.

   There is no interference effect from tailing in the analysis of small quantities of isomers.

   It provides accurate analytical values.

Application of CrownSil™ and CrownSil-Me™:

It is very effective in separating various amino acids and amine derivatives as follows.
If you need a detailed separation chromatogram, please contact us and we will provide it right away. (sales@cellachrom.co.kr)

* α-Amino Acids:

Alanine, arginine, asparagine, aspartic acid, cysteine, dopa, ethionine, glutamic acid, histidine, fluorophenylalalanine, leucine, lysine, methionine, norleucine, norvaline, phenylalanine, phenyliglycine, serine, threonine, 4-tyrosine, thyroxine, tryptophan, valine, etc.

* Amine:

1,2,3,4-tetrahydro-1-naphthylamine, 1-phenylethylamine, 1-naphthylamine, 2-naphthylamine, 4-methyl-[1,1'-biphenyl]-4-amine, 2-phenylethylamine, 3-methylaniline, 4-methylaniline, etc.

* Amino Alcohols:

2-Amino-1-phenylethanol, 4-(2-amino-1-hydroxyethyl)phenol, 4-(2-amino-1-hydroxyethyl)benzene-1,2-diol, 4-(2-amino-1-hydroxyethyl)-2-methoxyphenol, 2-amino-2-phenylethanol, 2-amino-2,3-dihydro-1H-indene-1-ol, 2-amino-1,2-diphenylethanol

* ß-blockers:

Acebutolol, Albuterol, Alprenolol, Atenolol, Bambuterol, Clenbuterol, Clenpropol, Fumoterol, Mabuterol, Oxprenolol, Pindolol, Propranolol.


- The CrownSil™ series is the new standard for crown ether chiral columns-

- Celachromium is the brand name of Celion Biomed Corporation. -

Contact: sales@cellachrim.co.kr


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Cellachrom™ is a HPLC column manufacture global leading brand

Cellachrom™  is a global leading brand developing bio & chemical substance analysis and separation technology, achieving the independence of cutting-edge HPLC column manufacture. Cellachrom is a company taking steps to become a leading company in chromatography products, supporting our customers with the best quality and reasonable prices. Based on our long-term research and development experience in the field of chirotechnology, we provide the best solutions for not only achiral analysis, but also chiral analysis and efficient separation. In addition, as an eco-friendly company considering global environment together with customer satisfaction, we are working to achieve carbon neutrality by establishing energy-saving technology in our manufacturing facilities, and are working on eco-friendly manufacturing with the goal of zero environmental pollution through recycling of the reagents generated in the process. We, CellaChrom, will always think of our customers and be eager to ...